He suffered from pancreatitis

In between his first and second trips to rehab, Perry wound up in the hospital for two weeks with acute pancreatitis and lost 20 pounds. The condition is reportedly caused by both alcohol abuse and prescription drug abuse.

“In my case, it was hard living and drinking hard and eating poorly,” he told Us Weekly (via E! News.) “You play, you pay. But there were no pills involved. I learned my lesson at Hazelden.”

Following his release from the hospital, Perry crashed his Porsche into an empty house. He was uninjured in the snafu, and neither drugs nor alcohol were found in his system at the time. “The irony was terrible,” he told Us Weekly of the awful day. “I was going to hang with my father at his place outside L.A. I made the first corner around my house on these really narrow streets, saw a courier van in the middle, swerved to the right and—well, I don’t really know what happened—I crashed into this porch.”

He made a third trip to rehab

Perry returned to rehab for a third time in 2011. He told TMZ he had not relapsed but was simply being proactive. “I’m making plans to go away for a month to focus on my sobriety and to continue my life in recovery,” he said. “Please enjoy making fun of me on the world wide web.”

From there, Perry began striving to advocate for others recovering from drug and alcohol abuse. Speaking with lawmakers, the actor said, “Drug courts are the single most effective program for curing serious drug addicts for lifelong recovery.” Talking to The Hill, Perry added, “Any opportunity I get to talk about drug courts on a one-on-one level or a much bigger level—like testifying in that scary room—I grab at because it’s just one of the few things that’s a no-brainer: it saves lives, it saves money, it’s bipartisan.”

He forgot three years of Friends

Three years of Friends are a little blurry for Perry. As he revealed in a BBC interview, he can’t remember a big chunk of the series because of his addiction. When asked what his least favorite episode was, Perry didn’t mince words. “Oh, my goodness,” he said. “I think the answer is, I don’t remember three years of it. So none of those… somewhere between season 3 and 6.”

Perry told People in 2013 that his struggles were hard to mask. “I couldn’t stop. Eventually things got so bad that I couldn’t hide it, and then everybody knew.” He said he never used drugs or abused alcohol while on set. “I was never high at work,” he said. “I was painfully hungover.”